6TL8
Structural basis of SALM3 dimerization and adhesion complex formation with the presynaptic receptor protein tyrosine phosphatases
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Myeloid cell surface antigen CD33,Leucine-rich repeat and fibronectin type-III domain-containing protein 4 | polymer | 299 | 32627.4 | 4 | UniProt (P20138) UniProt (Q80XU8) Pfam (PF13855) | Homo sapiens (Human) | Sialic acid-binding Ig-like lectin 3,Siglec-3,gp67 |
| 2 | E, F (C, D) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
| 3 | G, H, I, J (A, B, C, D) | water | water | 18.0 | 18 | Chemie (HOH) |
Sequence modifications
A, B, C, D: -3 - 12 (UniProt: P20138)
A, B, C, D: 17 - 284 (UniProt: Q80XU8)
| PDB | External Database | Details |
|---|---|---|
| Met 13 | - | linker |
| Asp 14 | - | linker |
| Lys 15 | - | linker |
| Leu 16 | - | linker |
| PDB | External Database | Details |
|---|---|---|
| Gly 285 | - | cloning artifact |
| Thr 286 | - | cloning artifact |
| Arg 287 | - | cloning artifact |
| Gly 288 | - | cloning artifact |
| Ser 289 | - | cloning artifact |
| Leu 290 | - | cloning artifact |
| Glu 291 | - | cloning artifact |
| Val 292 | - | cloning artifact |
| Leu 293 | - | cloning artifact |
| Phe 294 | - | cloning artifact |
| Gln 295 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 130509.8 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 442.4 | |
| All* | Total formula weight | 130952.2 |
