6TJ9

Escherichia coli transketolase in complex with cofactor analog 2'-methoxythiamine and substrate xylulose 5-phosphate

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Transketolase 1	polymer	669	73121.5	2	UniProt (P27302) Pfam (PF00456) Pfam (PF02779) Pfam (PF02780)	Escherichia coli (strain K12)	TK 1
2	C, V (A, B)	5-O-phosphono-D-xylulose	non-polymer		230.1	2	Chemie (5SP)
3	D, T (A, B)	2-[3-[(4-azanyl-2-methoxy-pyrimidin-5-yl)methyl]-4-methyl-1,3-thiazol-5-yl]ethyl phosphono hydrogen phosphate	non-polymer		441.3	2	Chemie (NDQ)
4	E, U (A, B)	CALCIUM ION	non-polymer		40.1	2	Chemie (CA)
5	AA, BA, CA, DA, EA... (B, A)	1,2-ETHANEDIOL	non-polymer		62.1	26	Chemie (EDO)
6	JA, S (B, A)	SODIUM ION	non-polymer		23.0	2	Chemie (NA)
7	KA, LA (A, B)	water	water		18.0	1525	Chemie (HOH)

Sequence modifications

A, B: 1 - 663 (UniProt: P27302)

PDB	External Database	Details
His 664	-	expression tag
His 665	-	expression tag
His 666	-	expression tag
His 667	-	expression tag
His 668	-	expression tag
His 669	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	146243.0
Non-Polymers*	Number of molecules	34
	Total formula weight	3082.8
All*	Total formula weight	149325.8

*Water molecules are not included.