6THV
X-ray structure of the Danio rerio histone deacetylase 6 (HDAC6; catalytic domain 2) in complex with Tubastatin A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Histone deacetylase 6 | polymer | 359 | 39899.1 | 1 | UniProt (F8W4B7) Pfam (PF00850) | Danio rerio (Zebrafish) | |
| 2 | B (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 3 | C, D, L (A) | POTASSIUM ION | non-polymer | 39.1 | 3 | Chemie (K) | |||
| 4 | E, F (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 5 | G, H (A) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 2 | Chemie (PEG) | |||
| 6 | I, J (A) | THIOCYANATE ION | non-polymer | 58.1 | 2 | Chemie (SCN) | |||
| 7 | K (A) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 8 | M (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 9 | N (A) | 4-[(2-methyl-3,4-dihydro-1~{H}-pyrido[4,3-b]indol-5-yl)methyl]-~{N}-oxidanyl-benzamide | non-polymer | 335.4 | 1 | Chemie (N9W) | |||
| 10 | O (A) | water | water | 18.0 | 369 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 39899.1 | |
| Non-Polymers* | Number of molecules | 13 |
| Total formula weight | 1085.7 | |
| All* | Total formula weight | 40984.9 |
