6TC0

Crystal structure of MMS19-CIAO1-CIAO2B CIA targeting complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D	Probable cytosolic iron-sulfur protein assembly protein Ciao1	polymer	338	37283.3	2	UniProt (Q7K1Y4) Pfam (PF00400) In PDB	Drosophila melanogaster (Fruit fly)
2	B, E	MIP18 family protein galla-2	polymer	159	17806.1	2	UniProt (Q9VTC4) Pfam (PF01883) In PDB	Drosophila melanogaster (Fruit fly)
3	C, F	MMS19 nucleotide excision repair protein homolog	polymer	1035	113534.0	2	UniProt (Q9D071) Pfam (PF12460) Pfam (PF14500) In PDB	Mus musculus (House mouse)	MET18 homolog,MMS19-like protein

Sequence modifications

A, D: 2 - 335 (UniProt: Q7K1Y4)

PDB	External Database	Details
Gly -2	-	expression tag
Gly -1	-	expression tag
Gly 0	-	expression tag
Arg 1	-	expression tag

B, E: 2 - 156 (UniProt: Q9VTC4)

PDB	External Database	Details
Gly -2	-	expression tag
Gly -1	-	expression tag
Gly 0	-	expression tag
Arg 1	-	expression tag

C, F: 1 - 1031 (UniProt: Q9D071)

PDB	External Database	Details
Gly -3	-	expression tag
Gly -2	-	expression tag
Gly -1	-	expression tag
Arg 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	337246.8
All*	Total formula weight	337246.8

*Water molecules are not included.