6TC0

Crystal structure of MMS19-CIAO1-CIAO2B CIA targeting complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005515	molecular_function	protein binding
A	0016226	biological_process	iron-sulfur cluster assembly
A	0097361	cellular_component	cytosolic [4Fe-4S] assembly targeting complex
B	0003674	molecular_function	molecular_function
B	0005515	molecular_function	protein binding
B	0007059	biological_process	chromosome segregation
B	0051301	biological_process	cell division
B	0097361	cellular_component	cytosolic [4Fe-4S] assembly targeting complex
B	0097428	biological_process	protein maturation by iron-sulfur cluster transfer
B	0106035	biological_process	protein maturation by [4Fe-4S] cluster transfer
C	0003713	molecular_function	transcription coactivator activity
C	0005634	cellular_component	nucleus
C	0005654	cellular_component	nucleoplasm
C	0005737	cellular_component	cytoplasm
C	0005819	cellular_component	spindle
C	0005829	cellular_component	cytosol
C	0005856	cellular_component	cytoskeleton
C	0006281	biological_process	DNA repair
C	0007059	biological_process	chromosome segregation
C	0019899	molecular_function	enzyme binding
C	0030331	molecular_function	nuclear estrogen receptor binding
C	0045893	biological_process	positive regulation of DNA-templated transcription
C	0071817	cellular_component	MMXD complex
C	0097361	cellular_component	cytosolic [4Fe-4S] assembly targeting complex
C	0097428	biological_process	protein maturation by iron-sulfur cluster transfer
D	0005515	molecular_function	protein binding
D	0016226	biological_process	iron-sulfur cluster assembly
D	0097361	cellular_component	cytosolic [4Fe-4S] assembly targeting complex
E	0003674	molecular_function	molecular_function
E	0005515	molecular_function	protein binding
E	0007059	biological_process	chromosome segregation
E	0051301	biological_process	cell division
E	0097361	cellular_component	cytosolic [4Fe-4S] assembly targeting complex
E	0097428	biological_process	protein maturation by iron-sulfur cluster transfer
E	0106035	biological_process	protein maturation by [4Fe-4S] cluster transfer
F	0003713	molecular_function	transcription coactivator activity
F	0005634	cellular_component	nucleus
F	0005654	cellular_component	nucleoplasm
F	0005737	cellular_component	cytoplasm
F	0005819	cellular_component	spindle
F	0005829	cellular_component	cytosol
F	0005856	cellular_component	cytoskeleton
F	0006281	biological_process	DNA repair
F	0007059	biological_process	chromosome segregation
F	0019899	molecular_function	enzyme binding
F	0030331	molecular_function	nuclear estrogen receptor binding
F	0045893	biological_process	positive regulation of DNA-templated transcription
F	0071817	cellular_component	MMXD complex
F	0097361	cellular_component	cytosolic [4Fe-4S] assembly targeting complex
F	0097428	biological_process	protein maturation by iron-sulfur cluster transfer

Functional Information from PROSITE/UniProt

site_id	PS00435
Number of Residues	11
Details	PEROXIDASE_1 Peroxidases proximal heme-ligand signature. EAEGLAALHSL

Chain	Residue	Details
C	GLU319-LEU329

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site_id	PS00678
Number of Residues	15
Details	WD_REPEATS_1 Trp-Asp (WD) repeats signature. LATCsrDkSVWIWEV

Chain	Residue	Details
A	LEU118-VAL132

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	MOD_RES: N-acetylalanine => ECO:0000250|UniProtKB:Q96T76

Chain	Residue	Details
C	ALA2
F	ALA2

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site_id	SWS_FT_FI2
Number of Residues	2
Details	MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:Q96T76

Chain	Residue	Details
C	SER1028
F	SER1028

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