6TBL

Crystal structure of MMS19(CTD)-CIAO1-CIAO2B CIA targeting complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	MMS19 nucleotide excision repair protein homolog	polymer	125	13570.0	2	UniProt (Q9D071)	Mus musculus (Mouse)	MET18 homolog,MMS19-like protein
2	C, D (C, D)	MIP18 family protein galla-2	polymer	159	17806.1	2	UniProt (Q9VTC4) Pfam (PF01883)	Drosophila melanogaster (Fruit fly)
3	E, F (E, F)	Probable cytosolic iron-sulfur protein assembly protein Ciao1	polymer	338	37283.3	2	UniProt (Q7K1Y4) Pfam (PF00400)	Drosophila melanogaster (Fruit fly)
4	G, H (A, B)	POTASSIUM ION	non-polymer		39.1	2	Chemie (K)
5	I, J, K (C, D)	1,2-ETHANEDIOL	non-polymer		62.1	3	Chemie (EDO)
6	L, M, N, O (B, C, D, F)	water	water		18.0	10	Chemie (HOH)

Sequence modifications

A, B: 911 - 1031 (UniProt: Q9D071)

PDB	External Database	Details
Gly 907	-	expression tag
Gly 908	-	expression tag
Gly 909	-	expression tag
Arg 910	-	expression tag

C, D: 2 - 156 (UniProt: Q9VTC4)

PDB	External Database	Details
Gly -2	-	expression tag
Gly -1	-	expression tag
Gly 0	-	expression tag
Arg 1	-	expression tag

E, F: 2 - 335 (UniProt: Q7K1Y4)

PDB	External Database	Details
Gly -2	-	expression tag
Gly -1	-	expression tag
Gly 0	-	expression tag
Arg 1	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	137318.9
Non-Polymers*	Number of molecules	5
	Total formula weight	264.4
All*	Total formula weight	137583.3

*Water molecules are not included.