6TBL
Crystal structure of MMS19(CTD)-CIAO1-CIAO2B CIA targeting complex
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0051604 | biological_process | protein maturation |
| B | 0051604 | biological_process | protein maturation |
| C | 0005515 | molecular_function | protein binding |
| C | 0005829 | cellular_component | cytosol |
| C | 0007059 | biological_process | chromosome segregation |
| C | 0044572 | biological_process | [4Fe-4S] cluster assembly |
| C | 0051301 | biological_process | cell division |
| C | 0051604 | biological_process | protein maturation |
| C | 0097361 | cellular_component | cytosolic [4Fe-4S] assembly targeting complex |
| C | 0140132 | molecular_function | iron-sulfur cluster chaperone activity |
| D | 0005515 | molecular_function | protein binding |
| D | 0005829 | cellular_component | cytosol |
| D | 0007059 | biological_process | chromosome segregation |
| D | 0044572 | biological_process | [4Fe-4S] cluster assembly |
| D | 0051301 | biological_process | cell division |
| D | 0051604 | biological_process | protein maturation |
| D | 0097361 | cellular_component | cytosolic [4Fe-4S] assembly targeting complex |
| D | 0140132 | molecular_function | iron-sulfur cluster chaperone activity |
| E | 0005515 | molecular_function | protein binding |
| E | 0005829 | cellular_component | cytosol |
| E | 0016226 | biological_process | iron-sulfur cluster assembly |
| E | 0044572 | biological_process | [4Fe-4S] cluster assembly |
| E | 0051604 | biological_process | protein maturation |
| E | 0097361 | cellular_component | cytosolic [4Fe-4S] assembly targeting complex |
| E | 0140132 | molecular_function | iron-sulfur cluster chaperone activity |
| F | 0005515 | molecular_function | protein binding |
| F | 0005829 | cellular_component | cytosol |
| F | 0016226 | biological_process | iron-sulfur cluster assembly |
| F | 0044572 | biological_process | [4Fe-4S] cluster assembly |
| F | 0051604 | biological_process | protein maturation |
| F | 0097361 | cellular_component | cytosolic [4Fe-4S] assembly targeting complex |
| F | 0140132 | molecular_function | iron-sulfur cluster chaperone activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | binding site for residue K A 1101 |
| Chain | Residue |
| A | THR983 |
| A | LEU985 |
| A | THR987 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | binding site for residue K B 1101 |
| Chain | Residue |
| B | THR983 |
| B | LEU985 |
| B | THR987 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue EDO C 201 |
| Chain | Residue |
| C | PHE34 |
| C | ILE68 |
| C | ASP70 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue EDO C 202 |
| Chain | Residue |
| C | SER74 |
| C | VAL75 |
| C | HIS76 |
| C | THR111 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue EDO D 201 |
| Chain | Residue |
| D | SER74 |
| D | VAL75 |
| D | HIS76 |
| D | HOH303 |
Functional Information from PROSITE/UniProt
| site_id | PS00678 |
| Number of Residues | 15 |
| Details | WD_REPEATS_1 Trp-Asp (WD) repeats signature. LATCsrDkSVWIWEV |
| Chain | Residue | Details |
| E | LEU118-VAL132 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 76 |
| Details | Repeat: {"description":"HEAT 3"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 76 |
| Details | Repeat: {"description":"HEAT 4"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"Q96T76","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 78 |
| Details | Repeat: {"description":"WD 1"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 78 |
| Details | Repeat: {"description":"WD 2"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 78 |
| Details | Repeat: {"description":"WD 3"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 78 |
| Details | Repeat: {"description":"WD 4"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 78 |
| Details | Repeat: {"description":"WD 5"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 78 |
| Details | Repeat: {"description":"WD 6"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI10 |
| Number of Residues | 68 |
| Details | Repeat: {"description":"WD 7"} |
| Chain | Residue | Details |
