6T6F
Crystal structure of human calmodulin-dependent protein kinase 1D (CAMK1D) bound to compound 8 (CS275)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Calcium/calmodulin-dependent protein kinase type 1D | polymer | 322 | 36699.0 | 2 | UniProt (Q8IU85) Pfam (PF00069) | Homo sapiens (Human) | CaM kinase I delta,CaMKID,CaMKI-like protein kinase,CKLiK |
| 2 | C, D (A, B) | 2-[(3~{S})-3-azanylpiperidin-1-yl]-4-[[3-(trifluoromethyl)phenyl]amino]pyrimidine-5-carboxamide | non-polymer | 380.4 | 2 | Chemie (MMW) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 206 | Chemie (HOH) |
Sequence modifications
A, B: 10 - 328 (UniProt: Q8IU85)
| PDB | External Database | Details |
|---|---|---|
| Ser 8 | - | expression tag |
| Met 9 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 73398.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 760.7 | |
| All* | Total formula weight | 74158.7 |
