6T5J
Structure of NUDT15 in complex with inhibitor TH1760
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Probable 8-oxo-dGTP diphosphatase NUDT15 | polymer | 164 | 18635.0 | 2 | UniProt (Q9NV35) Pfam (PF00293) In PDB | Homo sapiens (Human) | 8-oxo-dGTPase NUDT15,7,8-dihydro-8-oxoguanine-triphosphatase NUDT15,MutT homolog 2,MTH2,Nucleoside diphosphate-linked moiety X motif 15,Nudix motif 15 |
| 2 | A, B | 6-[4-(1~{H}-indol-5-ylcarbonyl)piperazin-1-yl]sulfonyl-3~{H}-1,3-benzoxazol-2-one | non-polymer | 426.4 | 2 | Chemie (MKB) | |||
| 3 | A, B | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
| 4 | A, B | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 5 | water | water | 18.0 | 454 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 37270.0 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1021.0 | |
| All* | Total formula weight | 38291.0 |
