6SXF
Crystal Structure of the Voltage-Gated Sodium Channel NavMs (F208L) in complex with Tamoxifen (2.8 Angstrom resolution)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Ion transport protein | polymer | 277 | 31185.7 | 2 | UniProt (A0L5S6) Pfam (PF00520) | Magnetococcus marinus MC-1 | |
| 2 | C, D, E, J, K... (A, B) | SODIUM ION | non-polymer | 23.0 | 6 | Chemie (NA) | |||
| 3 | F, H, M, O (A, B) | HEGA-10 | non-polymer | 379.5 | 4 | Chemie (2CV) | |||
| 4 | G, N (A, B) | DODECAETHYLENE GLYCOL | non-polymer | 546.6 | 2 | Chemie (12P) | |||
| 5 | I, P, Q (A, B) | (Z)-2-[4-(1,2)-DIPHENYL-1-BUTENYL)-PHENOXY]-N,N-DIMETHYLETHANAMINE | non-polymer | 371.5 | 3 | Chemie (CTX) | |||
| 6 | R, S (A, B) | water | water | 18.0 | 135 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 274 (UniProt: A0L5S6)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| His 0 | - | expression tag |
| Leu 208 | Phe 208 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 62371.5 | |
| Non-Polymers* | Number of molecules | 15 |
| Total formula weight | 3863.7 | |
| All* | Total formula weight | 66235.2 |
