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6SUH

Crystal structure of human transthyretin in complex with 3-O-methyltolcapone, a tolcapone analogue

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Transthyretinpolymer14715905.02UniProt (P02766)
Pfam (PF00576)
Homo sapiens (Human)ATTR,Prealbumin,TBPA
2C, D
(A, B)
3-O-methyltolcaponenon-polymer287.32Chemie (LVE)
3E, F
(A, B)
waterwater18.0190Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight31810.0
Non-Polymers*Number of molecules2
Total formula weight574.5
All*Total formula weight32384.5
*Water molecules are not included.

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PDB entries from 2025-06-18

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