6SP7

Crystal Structure of the VIM-2 Acquired Metallo-beta-Lactamase in Complex with Taniborbactam (VNRX-5133)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, E)	Metallo-beta-lactamase VIM-2	polymer	230	24522.2	2	UniProt (S5M6K4) Pfam (PF00753) UniProt (by SIFTS) (Q9K2N0)	Pseudomonas aeruginosa
2	C, D, E, I, J... (A, E)	ZINC ION	non-polymer		65.4	6	Chemie (ZN)
3	F, G, L, M (A, E)	ACETATE ION	non-polymer		59.0	4	Chemie (ACT)
4	H, N (A, E)	(4~{R})-4-[2-[4-(2-azanylethylamino)cyclohexyl]ethanoylamino]-3,3-bis(oxidanyl)-2-oxa-3-boranuidabicyclo[4.4.0]deca-1(10),6,8-triene-10-carboxylic acid	non-polymer		406.3	2	Chemie (K9B)
5	O, P (A, E)	water	water		18.0	200	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	49044.5
Non-Polymers*	Number of molecules	12
	Total formula weight	1441.2
All*	Total formula weight	50485.6

*Water molecules are not included.