6SJ7
Structure of the human DDB1-DDA1-DCAF15 E3 ubiquitin ligase bound to RBM39 and Indisulam
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | DDB1- and CUL4-associated factor 15 | polymer | 601 | 66563.3 | 1 | UniProt (Q66K64) Pfam (PF14939) In PDB | Homo sapiens (Human) | |
| 2 | B | DNA damage-binding protein 1 | polymer | 1140 | 127097.5 | 1 | UniProt (Q16531) Pfam (PF10433) Pfam (PF03178) In PDB | Homo sapiens (Human) | DDB p127 subunit,DNA damage-binding protein a,DDBa,Damage-specific DNA-binding protein 1,HBV X-associated protein 1,XAP-1,UV-damaged DNA-binding factor,UV-damaged DNA-binding protein 1,UV-DDB 1,XPE-binding factor,XPE-BF,Xeroderma pigmentosum group E-complementing protein,XPCe |
| 3 | C | RNA binding protein 39 | polymer | 81 | 9085.4 | 1 | UniProt (Q7Z3L0) Pfam (PF00076) UniProt (by SIFTS) (Q14498) In PDB | Homo sapiens (Human) | |
| 4 | D | DET1- and DDB1-associated protein 1 | polymer | 101 | 11724.1 | 1 | UniProt (Q9BW61) Pfam (PF10172) In PDB | Homo sapiens (Human) | Placenta cross-immune reaction antigen 1,PCIA-1 |
| 5 | A | N~1~-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonamide | non-polymer | 385.8 | 1 | Chemie (EF6) |
Sequence modifications
A: 1 - 600 (UniProt: Q66K64)
| PDB | External Database | Details |
|---|---|---|
| Gly 0 | - | expression tag |
| Pro 1 | Met 1 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 214470.3 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 385.8 | |
| All* | Total formula weight | 214856.1 |
