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6SH2

Crystal structure of human neprilysin E584D in complex with C-type natriuretic peptide.

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1AAANeprilysinpolymer69679511.51UniProt (P08473)
Pfam (PF05649)
Pfam (PF01431)
In PDB
Homo sapiens (Human)Atriopeptidase,Common acute lymphocytic leukemia antigen,CALLA,Enkephalinase,Neutral endopeptidase 24.11,Neutral endopeptidase,Skin fibroblast elastase,SFE
2DDDC-type natriuretic peptide fragment (CNP)polymer4302.31Homo sapiens
3AAA2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.24Chemie (NAG)
4AAAZINC IONnon-polymer65.41Chemie (ZN)
5AAACHLORIDE IONnon-polymer35.52Chemie (CL)
6waterwater18.01Chemie (HOH)
Sequence modifications
AAA: 54 - 749 (UniProt: P08473)
PDBExternal DatabaseDetails
Asp 584Glu 585engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight79813.8
Non-Polymers*Number of molecules7
Total formula weight1021.1
All*Total formula weight80834.9
*Water molecules are not included.

217705

PDB entries from 2024-03-27

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