6SH1
Crystal structure of substrate-free human neprilysin E584D.
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (AAA, CCC) | Neprilysin | polymer | 696 | 79511.5 | 2 | UniProt (P08473) Pfam (PF05649) Pfam (PF01431) | Homo sapiens (Human) | Atriopeptidase,Common acute lymphocytic leukemia antigen,CALLA,Enkephalinase,Neutral endopeptidase 24.11,Neutral endopeptidase,Skin fibroblast elastase,SFE |
| 2 | C, D, E, F, I... (AAA, CCC) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 8 | Chemie (NAG) | |||
| 3 | G, M, N (AAA, CCC) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
| 4 | H, O (AAA, CCC) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 5 | P, Q (AAA, CCC) | water | water | 18.0 | 495 | Chemie (HOH) |
Sequence modifications
AAA, CCC: 54 - 749 (UniProt: P08473)
| PDB | External Database | Details |
|---|---|---|
| Asp 584 | Glu 585 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 159023.0 | |
| Non-Polymers* | Number of molecules | 13 |
| Total formula weight | 2086.7 | |
| All* | Total formula weight | 161109.6 |
