6S5V
Crystal structure of the Cap-Midlink region of the H5N1 Influenza A virus polymerase in complex with a Cap-domain binding analogue
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (AAAA, ABAA) | Polymerase basic protein 2 | polymer | 304 | 34249.2 | 2 | UniProt (Q6E3N3) Pfam (PF20950) Pfam (PF00604) | Influenza A virus (A/duck/Fujian/13/2002(H5N1)) | RNA-directed RNA polymerase subunit P3 |
| 2 | C, F, H (AAAA, ABAA) | (1~{S},2~{S},3~{S},6~{R})-2-[[2-[5,7-bis(fluoranyl)-1~{H}-indol-3-yl]-5-fluoranyl-pyrimidin-4-yl]amino]-3,6-dimethyl-cyclohexane-1-carboxylic acid | non-polymer | 418.4 | 3 | Chemie (KWN) | |||
| 3 | D, E, G (AAAA, ABAA) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 4 | I (ABAA) | POTASSIUM ION | non-polymer | 39.1 | 1 | Chemie (K) | |||
| 5 | J, K (AAAA, ABAA) | water | water | 18.0 | 421 | Chemie (HOH) |
Sequence modifications
AAAA, ABAA: 247 - 536 (UniProt: Q6E3N3)
| PDB | External Database | Details |
|---|---|---|
| His 233 | - | expression tag |
| His 234 | - | expression tag |
| His 235 | - | expression tag |
| His 236 | - | expression tag |
| His 237 | - | expression tag |
| His 238 | - | expression tag |
| Gly 239 | - | expression tag |
| Glu 240 | - | expression tag |
| Asn 241 | - | expression tag |
| Leu 242 | - | expression tag |
| Tyr 243 | - | expression tag |
| Phe 244 | - | expression tag |
| Gln 245 | - | expression tag |
| Gly 246 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 68498.3 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1570.6 | |
| All* | Total formula weight | 70069.0 |
