6RPN
Structure of metallo beta lactamase VIM-2 with cyclic boronate APC308.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Beta-lactamase VIM-2 | polymer | 242 | 25693.5 | 2 | UniProt (Q9K2N0) Pfam (PF00753) | Pseudomonas aeruginosa | Class B beta-lactamase,Class B carbapenemase VIM-2,Metallo beta lactamase VIM-2,Metallo beta-lactamase,Metallo-beta-lactamase VIM-2,Metallo-beta-lactamase vim-2,Mettalo-beta-lactamase VIM-2,VIM-2 metallo-beta-lactamase,VIM-2 protein |
| 2 | C, J (A, B) | (3~{R})-2,2-bis(oxidanyl)-3-(phenylmethylsulfanyl)-3,4-dihydro-1,2-benzoxaborinin-2-ium-8-carboxylic acid | non-polymer | 331.2 | 2 | Chemie (KDZ) | |||
| 3 | D, K (A, B) | (3~{S})-2,2-bis(oxidanyl)-3-(phenylmethylsulfanyl)-3,4-dihydro-1,2-benzoxaborinin-2-ium-8-carboxylic acid | non-polymer | 331.2 | 2 | Chemie (KL8) | |||
| 4 | E, F, G, L, M... (A, B) | ZINC ION | non-polymer | 65.4 | 6 | Chemie (ZN) | |||
| 5 | H, I, O, P (A, B) | CHLORIDE ION | non-polymer | 35.5 | 4 | Chemie (CL) | |||
| 6 | Q, R (B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 7 | S (B) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 8 | T, U (A, B) | water | water | 18.0 | 695 | Chemie (HOH) |
Sequence modifications
A, B: 27 - 266 (UniProt: Q9K2N0)
| PDB | External Database | Details |
|---|---|---|
| Gly 25 | - | expression tag |
| Pro 26 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 51387.0 | |
| Non-Polymers* | Number of molecules | 17 |
| Total formula weight | 1999.7 | |
| All* | Total formula weight | 53386.6 |
