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6RPN

Structure of metallo beta lactamase VIM-2 with cyclic boronate APC308.

Functional Information from GO Data
ChainGOidnamespacecontents
A0016787molecular_functionhydrolase activity
A0017001biological_processantibiotic catabolic process
A0042597cellular_componentperiplasmic space
A0046677biological_processresponse to antibiotic
A0046872molecular_functionmetal ion binding
B0016787molecular_functionhydrolase activity
B0017001biological_processantibiotic catabolic process
B0042597cellular_componentperiplasmic space
B0046677biological_processresponse to antibiotic
B0046872molecular_functionmetal ion binding
Functional Information from PDB Data
site_idAC1
Number of Residues17
Detailsbinding site for residue KDZ A 301
ChainResidue
APHE62
AASN210
AASP213
AHIS240
AKL8302
AZN304
AZN305
AHOH409
AHOH423
ATYR67
ATRP87
AHIS114
AHIS116
AASP118
AHIS179
ACYS198
AGLY209

site_idAC2
Number of Residues17
Detailsbinding site for residue KL8 A 302
ChainResidue
APHE62
ATYR67
ATRP87
AHIS114
AHIS116
AASP118
AHIS179
ACYS198
AGLY209
AASN210
AHIS240
AKDZ301
AZN304
AZN305
AHOH409
AHOH423
AHOH558

site_idAC3
Number of Residues2
Detailsbinding site for residue ZN A 303
ChainResidue
AHIS153
ACL306

site_idAC4
Number of Residues5
Detailsbinding site for residue ZN A 304
ChainResidue
AHIS114
AHIS116
AHIS179
AKDZ301
AKL8302

site_idAC5
Number of Residues5
Detailsbinding site for residue ZN A 305
ChainResidue
AASP118
ACYS198
AHIS240
AKDZ301
AKL8302

site_idAC6
Number of Residues2
Detailsbinding site for residue CL A 306
ChainResidue
AHIS153
AZN303

site_idAC7
Number of Residues2
Detailsbinding site for residue CL A 307
ChainResidue
AHIS251
AASN254

site_idAC8
Number of Residues19
Detailsbinding site for residue KDZ B 501
ChainResidue
BPHE62
BTYR67
BTRP87
BHIS114
BHIS116
BASP118
BHIS179
BCYS198
BARG205
BGLY209
BASN210
BASP213
BHIS240
BKL8502
BZN503
BZN505
BHOH620
BHOH628
BHOH822

site_idAC9
Number of Residues17
Detailsbinding site for residue KL8 B 502
ChainResidue
BPHE62
BTYR67
BTRP87
BHIS114
BHIS116
BASP118
BHIS179
BCYS198
BARG205
BASN210
BHIS240
BKDZ501
BZN503
BZN505
BHOH620
BHOH628
BHOH786

site_idAD1
Number of Residues5
Detailsbinding site for residue ZN B 503
ChainResidue
BHIS114
BHIS116
BHIS179
BKDZ501
BKL8502

site_idAD2
Number of Residues4
Detailsbinding site for residue ZN B 504
ChainResidue
BHIS153
BHIS251
BCL506
BCL507

site_idAD3
Number of Residues5
Detailsbinding site for residue ZN B 505
ChainResidue
BKL8502
BASP118
BCYS198
BHIS240
BKDZ501

site_idAD4
Number of Residues7
Detailsbinding site for residue CL B 506
ChainResidue
BALA132
BHIS153
BHIS251
BASN254
BZN504
BCL507
BHOH866

site_idAD5
Number of Residues6
Detailsbinding site for residue CL B 507
ChainResidue
BHIS153
BHIS251
BASN254
BZN504
BCL506
BHOH618

site_idAD6
Number of Residues2
Detailsbinding site for residue MG B 508
ChainResidue
BGLY31
BHOH880

site_idAD7
Number of Residues5
Detailsbinding site for residue MG B 509
ChainResidue
AHOH742
BHOH745
BHOH813
BHOH841
BHOH896

site_idAD8
Number of Residues5
Detailsbinding site for residue GOL B 510
ChainResidue
BPRO106
BVAL107
BALA129
BHOH739
BHOH790

227344

PDB entries from 2024-11-13

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