6RLC
Crystal structure of the PDZ tandem of syntenin in complex with fragment F13
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Syntenin-1 | polymer | 166 | 18018.7 | 4 | UniProt (O00560) Pfam (PF00595) | Homo sapiens (Human) | Melanoma differentiation-associated protein 9,MDA-9,Pro-TGF-alpha cytoplasmic domain-interacting protein 18,TACIP18,Scaffold protein Pbp1,Syndecan-binding protein 1 |
| 2 | E, G, I, J (A, B, C, D) | (2~{S})-2-[3-(4-chlorophenyl)sulfanylpropanoylamino]-3-methyl-butanoic acid | non-polymer | 315.8 | 4 | Chemie (K7Z) | |||
| 3 | F, H, K (A, B, D) | ACETATE ION | non-polymer | 59.0 | 3 | Chemie (ACT) | |||
| 4 | L, M, N, O (A, B, C, D) | water | water | 18.0 | 148 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 113 - 273 (UniProt: O00560)
| PDB | External Database | Details |
|---|---|---|
| Gly 108 | - | expression tag |
| Ala 109 | - | expression tag |
| Met 110 | - | expression tag |
| Asp 111 | - | expression tag |
| Pro 112 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 72074.8 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1440.4 | |
| All* | Total formula weight | 73515.1 |
