6RLC
Crystal structure of the PDZ tandem of syntenin in complex with fragment F13
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0007268 | biological_process | chemical synaptic transmission |
| A | 0030036 | biological_process | actin cytoskeleton organization |
| A | 0035556 | biological_process | intracellular signal transduction |
| B | 0007268 | biological_process | chemical synaptic transmission |
| B | 0030036 | biological_process | actin cytoskeleton organization |
| B | 0035556 | biological_process | intracellular signal transduction |
| C | 0007268 | biological_process | chemical synaptic transmission |
| C | 0030036 | biological_process | actin cytoskeleton organization |
| C | 0035556 | biological_process | intracellular signal transduction |
| D | 0007268 | biological_process | chemical synaptic transmission |
| D | 0030036 | biological_process | actin cytoskeleton organization |
| D | 0035556 | biological_process | intracellular signal transduction |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 14 |
| Details | binding site for residue K7Z A 301 |
| Chain | Residue |
| A | HIS208 |
| A | LEU258 |
| D | SER259 |
| D | THR260 |
| D | SER261 |
| D | HOH419 |
| A | VAL209 |
| A | GLY210 |
| A | PHE211 |
| A | ILE212 |
| A | PHE213 |
| A | ASP251 |
| A | SER252 |
| A | ALA255 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | binding site for residue ACT A 302 |
| Chain | Residue |
| A | ILE125 |
| A | LEU127 |
| site_id | AC3 |
| Number of Residues | 15 |
| Details | binding site for residue K7Z B 301 |
| Chain | Residue |
| B | HIS208 |
| B | VAL209 |
| B | GLY210 |
| B | PHE211 |
| B | ILE212 |
| B | PHE213 |
| B | SER252 |
| B | ALA255 |
| B | LEU258 |
| B | HOH403 |
| B | HOH412 |
| C | LYS203 |
| C | SER259 |
| C | THR260 |
| C | SER261 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue ACT B 302 |
| Chain | Residue |
| B | ILE125 |
| B | GLY126 |
| B | LEU127 |
| B | ARG128 |
| B | LYS179 |
| site_id | AC5 |
| Number of Residues | 16 |
| Details | binding site for residue K7Z C 301 |
| Chain | Residue |
| B | SER259 |
| B | THR260 |
| B | SER261 |
| B | HOH428 |
| C | HIS208 |
| C | VAL209 |
| C | GLY210 |
| C | PHE211 |
| C | ILE212 |
| C | PHE213 |
| C | ASP251 |
| C | SER252 |
| C | ALA255 |
| C | LEU258 |
| C | HOH410 |
| C | HOH412 |
| site_id | AC6 |
| Number of Residues | 15 |
| Details | binding site for residue K7Z D 301 |
| Chain | Residue |
| A | LYS203 |
| A | SER259 |
| A | THR260 |
| A | SER261 |
| D | HIS208 |
| D | VAL209 |
| D | GLY210 |
| D | PHE211 |
| D | ILE212 |
| D | PHE213 |
| D | ASP251 |
| D | SER252 |
| D | ALA255 |
| D | LEU258 |
| D | HOH403 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue ACT D 302 |
| Chain | Residue |
| D | LYS124 |
| D | ILE125 |
| D | GLY126 |
| D | LEU127 |
Functional Information from PROSITE/UniProt
| site_id | PS00070 |
| Number of Residues | 12 |
| Details | ALDEHYDE_DEHYDR_CYS Aldehyde dehydrogenases cysteine active site. LqINGENCAGWS |
| Chain | Residue | Details |
| A | LEU159-SER170 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 8 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:27386966, ECO:0007744|PDB:4Z33 |
| Chain | Residue | Details |
| A | ASN215 | |
| A | LYS250 | |
| B | ASN215 | |
| B | LYS250 | |
| C | ASN215 | |
| C | LYS250 | |
| D | ASN215 | |
| D | LYS250 |
