6RA1
Human Cyclophilin D in complex with norbornane fragment derivative
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Peptidyl-prolyl cis-trans isomerase F, mitochondrial | polymer | 164 | 17652.1 | 1 | UniProt (P30405) Pfam (PF00160) In PDB | Homo sapiens (Human) | PPIase F,Cyclophilin D,CypD,Cyclophilin F,Mitochondrial cyclophilin,CyP-M,Rotamase F |
2 | A | 2-[(1~{R},2~{R},6~{S},7~{S})-3,5-bis(oxidanylidene)-4-azatricyclo[5.2.1.0^{2,6}]decan-4-yl]ethanoic acid | non-polymer | 223.2 | 1 | Chemie (JWB) | |||
3 | A | 14-ethyl-4,6-dioxa-10,14-diazatricyclo[7.6.0.0^{3,7}]pentadeca-1(9),2,7-trien-13-one | non-polymer | 248.3 | 1 | Chemie (JVQ) | |||
4 | A | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
5 | A | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 1 | Chemie (PG4) | |||
6 | A | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
7 | water | water | 18.0 | 79 | Chemie (HOH) |
Sequence modifications
A: 44 - 207 (UniProt: P30405)
PDB | External Database | Details |
---|---|---|
Ile 175 | Lys 175 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 17652.1 | |
Non-Polymers* | Number of molecules | 6 |
Total formula weight | 964.0 | |
All* | Total formula weight | 18616.1 |