6R9S
Human Cyclophilin D in complex with bicyclic fragment
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Peptidyl-prolyl cis-trans isomerase F, mitochondrial | polymer | 164 | 17652.1 | 1 | UniProt (P30405) Pfam (PF00160) | Homo sapiens (human) | PPIase F,Cyclophilin D,CypD,Cyclophilin F,Mitochondrial cyclophilin,CyP-M,Rotamase F |
| 2 | B, C (A) | (1~{R},9~{R},10~{S})-4-fluoranyl-12-oxa-8-azatricyclo[7.3.1.0^{2,7}]trideca-2(7),3,5-trien-10-ol | non-polymer | 209.2 | 2 | Chemie (JVN) | |||
| 3 | D (A) | PENTAETHYLENE GLYCOL | non-polymer | 238.3 | 1 | Chemie (1PE) | |||
| 4 | E (A) | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 1 | Chemie (PG4) | |||
| 5 | F (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 6 | G (A) | water | water | 18.0 | 200 | Chemie (HOH) |
Sequence modifications
A: 44 - 207 (UniProt: P30405)
| PDB | External Database | Details |
|---|---|---|
| Ile 175 | Lys 175 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 17652.1 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 947.0 | |
| All* | Total formula weight | 18599.1 |
