6R5G
C-SH2 domain of SHP-2 in complex with phospho-ITSM of PD-1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Tyrosine-protein phosphatase non-receptor type 11 | polymer | 119 | 13302.0 | 1 | UniProt (Q06124) Pfam (PF00017) | Homo sapiens (Human) | Protein-tyrosine phosphatase 1D,PTP-1D,Protein-tyrosine phosphatase 2C,PTP-2C,SH-PTP2,Shp2,SH-PTP3 |
| 2 | B (B) | ITSM | polymer | 11 | 1377.4 | 1 | UniProt (by SIFTS) (Q15116) | Homo sapiens |
Sequence modifications
A: 105 - 220 (UniProt: Q06124)
| PDB | External Database | Details |
|---|---|---|
| Gly 102 | - | expression tag |
| Pro 103 | - | expression tag |
| Met 104 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 14679.3 | |
| All* | Total formula weight | 14679.3 |
