6R5G
C-SH2 domain of SHP-2 in complex with phospho-ITSM of PD-1
Spectrometer
Experimental method: SOLUTION NMR
| Spectrometer ID | Spectrometer maker | Spectrometer model | Spectrometer type | Spectrometer field strength |
| 1 | Bruker | AVANCE III HD | 850 | |
| 2 | Bruker | AVANCE III HD | 600 |
Experiment
| experiment id | conditions id | solution id | Experiment type |
| 1 | 1 | 3 | 2D 1H-15N HSQC |
| 10 | 1 | 4 | 2D 13C/15N-filtered 1H-1H TOCSY |
| 11 | 1 | 3 | 3D NOESY-15N HSQC |
| 2 | 1 | 3 | 3D HNCO |
| 3 | 1 | 3 | 3D HNCACB |
| 4 | 1 | 3 | 3D HN(COCA)CB |
| 5 | 1 | 3 | 3D HCCH-TOCSY |
| 6 | 1 | 3 | 2D 1H-13C HSQC |
| 7 | 1 | 3 | 3D NOESY-13C HSQC |
| 8 | 1 | 3 | 3D 13C/15N-filtered NOESY-13C HSQC |
| 9 | 1 | 4 | 2D 13C/15N-filtered 1H-1H NOESY |
NMR Sample
| conditions id | NMR sample pH | NMR sample pressure | NMR sample temperature |
| 1 | 6.8 | 1 | 298 |
Conformers
| Conformers Calculated Total Number | 150 |
| Conformers Submitted Total Number | 10 |
