6R4V
Crystal structure of human geranylgeranyl diphosphate synthase bound to ibandronate
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C, F, E, B... | Geranylgeranyl pyrophosphate synthase | polymer | 307 | 35436.3 | 6 | UniProt (O95749) Pfam (PF00348) In PDB | Homo sapiens (Human) | GGPPSase,(2E,6E)-farnesyl diphosphate synthase,Dimethylallyltranstransferase,Farnesyl diphosphate synthase,Farnesyltranstransferase,Geranylgeranyl diphosphate synthase,Geranyltranstransferase |
2 | D, A, C, F, E... | MAGNESIUM ION | non-polymer | 24.3 | 17 | Chemie (MG) | |||
3 | B, D, A, C, F... | IBANDRONATE | non-polymer | 319.2 | 6 | Chemie (BFQ) | |||
4 | A, C | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
5 | water | water | 18.0 | 1242 | Chemie (HOH) |
Sequence modifications
A, C, F, E, B, D: 1 - 300 (UniProt: O95749)
PDB | External Database | Details |
---|---|---|
Gly -6 | - | expression tag |
Ser -5 | - | expression tag |
Gly -4 | - | expression tag |
Ser -3 | - | expression tag |
Gly -2 | - | expression tag |
Ser -1 | - | expression tag |
Gly 0 | - | expression tag |
Gln 109 | Pro 109 | variant |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 212617.7 | |
Non-Polymers* | Number of molecules | 25 |
Total formula weight | 2512.7 | |
All* | Total formula weight | 215130.4 |