6R0X
The extracellular domain of G6b-B in complex with Fab fragment and DP12 heparin oligosaccharide.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | antibody fab fragment heavy chain | polymer | 240 | 25761.9 | 2 | Homo sapiens | ||
| 2 | B, D (B, D) | antibody fab fragment light chain | polymer | 234 | 25848.6 | 2 | Homo sapiens | ||
| 3 | E, F (E, F) | Megakaryocyte and platelet inhibitory receptor G6b | polymer | 116 | 12408.2 | 2 | UniProt (O95866) Pfam (PF15096) | Homo sapiens (Human) | Protein G6b |
| 4 | G, I (G, I) | beta-D-galactopyranose-(1-3)-[N-acetyl-alpha-neuraminic acid-(2-6)]2-acetamido-2-deoxy-alpha-D-galactopyranose | branched | 674.6 | 2 | In PDB GlyTouCan (G56682BC) | |||
| 5 | H (H) | 2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose | branched | 2327.9 | 1 | In PDB GlyTouCan (G40559JB) |
Sequence modifications
E, F: 18 - 133 (UniProt: O95866)
| PDB | External Database | Details |
|---|---|---|
| Asp 32 | Asn 32 | engineered mutation |
| Ala 67 | Ser 67 | engineered mutation |
| Ala 68 | Ser 68 | engineered mutation |
| Ala 69 | Ser 69 | engineered mutation |
| Ala 71 | Thr 71 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 128037.4 | |
| Branched | Number of molecules | 3 |
| Total formula weight | 3677.1 | |
| All* | Total formula weight | 131714.5 |
