6QXS

Crystal structure of Enteroccocus faecalis thymidylate synthase (EfTS) in complex with FdUMP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Thymidylate synthase	polymer	315	36462.1	1	UniProt (Q834R3) Pfam (PF00303) In PDB	Enterococcus faecalis (strain ATCC 700802 / V583)	TSase
2	B, C, D	Thymidylate synthase	polymer	315	36386.0	3	UniProt (Q834R3) Pfam (PF00303) In PDB	Enterococcus faecalis	TSase
3	B, D	5-FLUORO-2'-DEOXYURIDINE-5'-MONOPHOSPHATE	non-polymer		326.2	2	Chemie (UFP)
4	B, D	SULFATE ION	non-polymer		96.1	2	Chemie (SO4)
5	B, D	N-[4-({[(6S)-2-amino-5-formyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamic acid	non-polymer		473.4	2	Chemie (FFO)
6		water	water		18.0	327	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	145620.0
Non-Polymers*	Number of molecules	6
	Total formula weight	1791.3
All*	Total formula weight	147411.4

*Water molecules are not included.