6QXS
Crystal structure of Enteroccocus faecalis thymidylate synthase (EfTS) in complex with FdUMP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Thymidylate synthase | polymer | 315 | 36462.1 | 1 | UniProt (Q834R3) Pfam (PF00303) | Enterococcus faecalis (strain ATCC 700802 / V583) | TSase |
| 2 | B, C, D (B, C, D) | Thymidylate synthase | polymer | 315 | 36386.0 | 3 | UniProt (Q834R3) Pfam (PF00303) | Enterococcus faecalis | TSase |
| 3 | E, H (B, D) | 5-FLUORO-2'-DEOXYURIDINE-5'-MONOPHOSPHATE | non-polymer | 326.2 | 2 | Chemie (UFP) | |||
| 4 | F, I (B, D) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 5 | G, J (B, D) | N-[4-({[(6S)-2-amino-5-formyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamic acid | non-polymer | 473.4 | 2 | Chemie (FFO) | |||
| 6 | K, L, M, N (A, B, C, D) | water | water | 18.0 | 327 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 145620.0 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1791.3 | |
| All* | Total formula weight | 147411.4 |
