6QLW

Cathepsin-K in complex with MIV-710

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D	Cathepsin K	polymer	216	23680.7	4	UniProt (P43235) Pfam (PF00112) In PDB	Homo sapiens (Human)	Cathepsin O,Cathepsin O2,Cathepsin X
2	A, B, C, D	~{N}-[(2~{S})-1-[(3~{R},3~{a}~{R},6~{R},6~{a}~{S})-6-chloranyl-3-oxidanyl-2,3,3~{a},5,6,6~{a}-hexahydrofuro[3,2-b]pyrrol-4-yl]-4-methyl-1-oxidanylidene-pentan-2-yl]-4-[5-fluoranyl-2-(4-methylpiperazin-1-yl)-1,3-thiazol-4-yl]benzamide	non-polymer		580.1	4	Chemie (J5T)
3	A, B, C, D	CHLORIDE ION	non-polymer		35.5	7	Chemie (CL)
4	A, C	SODIUM ION	non-polymer		23.0	2	Chemie (NA)
5		water	water		18.0	899	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	94722.7
Non-Polymers*	Number of molecules	13
	Total formula weight	2614.6
All*	Total formula weight	97337.3

*Water molecules are not included.