6QLW
Cathepsin-K in complex with MIV-710
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Cathepsin K | polymer | 216 | 23680.7 | 4 | UniProt (P43235) Pfam (PF00112) | Homo sapiens (Human) | Cathepsin O,Cathepsin O2,Cathepsin X |
| 2 | E, J, L, P (A, B, C, D) | ~{N}-[(2~{S})-1-[(3~{R},3~{a}~{R},6~{R},6~{a}~{S})-6-chloranyl-3-oxidanyl-2,3,3~{a},5,6,6~{a}-hexahydrofuro[3,2-b]pyrrol-4-yl]-4-methyl-1-oxidanylidene-pentan-2-yl]-4-[5-fluoranyl-2-(4-methylpiperazin-1-yl)-1,3-thiazol-4-yl]benzamide | non-polymer | 580.1 | 4 | Chemie (J5T) | |||
| 3 | F, G, H, K, M... (A, B, C, D) | CHLORIDE ION | non-polymer | 35.5 | 7 | Chemie (CL) | |||
| 4 | I, O (A, C) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 5 | R, S, T, U (A, B, C, D) | water | water | 18.0 | 899 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 94722.7 | |
| Non-Polymers* | Number of molecules | 13 |
| Total formula weight | 2614.6 | |
| All* | Total formula weight | 97337.3 |
