6QJU
Crystal structure of human Bromodomain containing protein 3 (BRD3) in complex with 3-bromo-1H-indazol-5-amine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Bromodomain-containing protein 3 | polymer | 123 | 14586.8 | 2 | UniProt (Q15059) Pfam (PF00439) | Homo sapiens (Human) | RING3-like protein |
| 2 | C, D, G (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
| 3 | E (A) | THIOCYANATE ION | non-polymer | 58.1 | 1 | Chemie (SCN) | |||
| 4 | F (A) | 3-bromanyl-2~{H}-indazol-5-amine | non-polymer | 212.0 | 1 | Chemie (J58) | |||
| 5 | H (B) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) | |||
| 6 | I, J (B) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 7 | K, L (A, B) | water | water | 18.0 | 264 | Chemie (HOH) |
Sequence modifications
A, B: 24 - 144 (UniProt: Q15059)
| PDB | External Database | Details |
|---|---|---|
| Ser 22 | - | expression tag |
| Met 23 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 29173.7 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 580.4 | |
| All* | Total formula weight | 29754.1 |
