6PT1
Crystal Structure of Class D Beta-lactamase OXA-48 with Meropenem
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | Class D Carbapenemase OXA-48 | polymer | 263 | 30826.9 | 4 | UniProt (A0A482LRD5) Pfam (PF00905) UniProt (by SIFTS) (Q6XEC0) In PDB | Klebsiella pneumoniae | |
2 | A, B, C, D | CHLORIDE ION | non-polymer | 35.5 | 6 | Chemie (CL) | |||
3 | A, B, C, D | (4R,5S)-3-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-5-[(2S,3R)-3-hydroxy-1-oxobutan-2-yl]-4-methyl-4,5-d ihydro-1H-pyrrole-2-carboxylic acid | non-polymer | 385.5 | 4 | Chemie (MER) | |||
4 | C, D | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
5 | water | water | 18.0 | 544 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 25 - 265 (UniProt: A0A482LRD5)
PDB | External Database | Details |
---|---|---|
Met 3 | - | initiating methionine |
Lys 4 | - | expression tag |
His 5 | - | expression tag |
His 6 | - | expression tag |
His 7 | - | expression tag |
His 8 | - | expression tag |
His 9 | - | expression tag |
His 10 | - | expression tag |
Met 11 | - | expression tag |
His 12 | - | expression tag |
His 13 | - | expression tag |
His 14 | - | expression tag |
His 15 | - | expression tag |
His 16 | - | expression tag |
His 17 | - | expression tag |
Glu 18 | - | expression tag |
Asn 19 | - | expression tag |
Leu 20 | - | expression tag |
Tyr 21 | - | expression tag |
Phe 22 | - | expression tag |
Gln 23 | - | expression tag |
Gly 24 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 123307.5 | |
Non-Polymers* | Number of molecules | 12 |
Total formula weight | 1938.8 | |
All* | Total formula weight | 125246.3 |