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6PKX

Cryo-EM structure of the zebrafish TRPM2 channel in the presence of ADPR and Ca2+

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
Transient receptor potential cation channel subfamily M member 2polymer1466167608.64Pfam (PF18139)
Pfam (PF00520)
UniProt (by SIFTS) (A0A0R4IMY7)
Danio rerio (Zebrafish)
2E, G
(B, D)
CALCIUM IONnon-polymer40.12Chemie (CA)
3F, H
(B, D)
[(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL [HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATEnon-polymer559.32Chemie (AR6)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight670434.5
Non-Polymers*Number of molecules4
Total formula weight1198.8
All*Total formula weight671633.3
*Water molecules are not included.

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PDB entries from 2025-07-16

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