6PKD
Myocilin OLF mutant N428D/D478H
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Myocilin | polymer | 277 | 31221.0 | 2 | UniProt (Q99972) Pfam (PF02191) | Homo sapiens | Myocilin 55 kDa subunit,Trabecular meshwork-induced glucocorticoid response protein |
| 2 | C, D (A, B) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 338 | Chemie (HOH) |
Sequence modifications
A, B: 228 - 504 (UniProt: Q99972)
| PDB | External Database | Details |
|---|---|---|
| Asp 428 | Asn 428 | engineered mutation |
| His 478 | Asp 478 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 62442.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 46.0 | |
| All* | Total formula weight | 62488.0 |
