6PKD
Myocilin OLF mutant N428D/D478H
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0001952 | biological_process | regulation of cell-matrix adhesion |
| A | 0005615 | cellular_component | extracellular space |
| A | 0030335 | biological_process | positive regulation of cell migration |
| A | 0051492 | biological_process | regulation of stress fiber assembly |
| B | 0001952 | biological_process | regulation of cell-matrix adhesion |
| B | 0005615 | cellular_component | extracellular space |
| B | 0030335 | biological_process | positive regulation of cell migration |
| B | 0051492 | biological_process | regulation of stress fiber assembly |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue NA A 601 |
| Chain | Residue |
| A | ASP380 |
| A | ASP428 |
| A | HOH702 |
| A | HOH707 |
| A | HOH719 |
| A | HOH830 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue NA B 601 |
| Chain | Residue |
| B | HOH742 |
| B | HOH776 |
| B | ASP380 |
| B | ASP428 |
| B | HOH708 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Motif: {"description":"Microbody targeting signal","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 10 |
| Details | Binding site: {"evidences":[{"source":"PDB","id":"4WXQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4WXS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4WXU","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
