6PIB

Structure of the Klebsiella pneumoniae LpxH-AZ1 complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	UDP-2,3-diacylglucosamine hydrolase	polymer	260	29726.8	1	UniProt (A0A1S0WIC1) Pfam (PF00149) UniProt (by SIFTS) (A6T5R0) In PDB	Klebsiella pneumoniae	UDP-2,3-diacylglucosamine diphosphatase
2	A	MANGANESE (II) ION	non-polymer		54.9	2	Chemie (MN)
3	A	1-[5-({4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}sulfonyl)-2,3-dihydro-1H-indol-1-yl]ethan-1-one	non-polymer		453.5	1	Chemie (OKV)
4	A	TETRAETHYLENE GLYCOL	non-polymer		194.2	3	Chemie (PG4)
5		water	water		18.0	46	Chemie (HOH)

Sequence modifications

A: 0 - 240 (UniProt: A0A1S0WIC1)

PDB	External Database	Details
Val 1	-	insertion
Leu 241	-	expression tag
Glu 242	-	expression tag
Glu 243	-	expression tag
Asn 244	-	expression tag
Leu 245	-	expression tag
Tyr 246	-	expression tag
Phe 247	-	expression tag
Gln 248	-	expression tag
Ser 249	-	expression tag
His 250	-	expression tag
His 251	-	expression tag
His 252	-	expression tag
His 253	-	expression tag
His 254	-	expression tag
His 255	-	expression tag
His 256	-	expression tag
His 257	-	expression tag
His 258	-	expression tag
His 259	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	29726.8
Non-Polymers*	Number of molecules	6
	Total formula weight	1146.0
All*	Total formula weight	30872.8

*Water molecules are not included.