6PHB

Pfs25 in complex with the human transmission blocking antibody 2530

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D (I, E)	25 kDa ookinete surface antigen	polymer	184	20233.3	2	UniProt (P13829) Pfam (PF06247)	Plasmodium falciparum	Pfs25
2	B, E (C, A)	2530 Antibody Fab, Light Chain	polymer	215	23625.1	2		Homo sapiens (Human)
3	C, F (D, B)	2530 Antibody Fab, Heavy Chain	polymer	220	23310.0	2		Homo sapiens (Human)
4	G, H, I, J, K... (I, C, D, A, B)	1,2-ETHANEDIOL	non-polymer		62.1	16	Chemie (EDO)
5	AA, BA, W, X, Y... (A, B, I, C, D...)	water	water		18.0	1057	Chemie (HOH)

Sequence modifications

I, E: 1 - 172 (UniProt: P13829)

PDB	External Database	Details
Glu -2	-	expression tag
Thr -1	-	expression tag
Gly 0	-	expression tag
Gln 91	Asn 112	conflict
Gln 144	Asn 165	conflict
Gln 166	Asn 187	conflict
Gly 173	-	expression tag
Thr 174	-	expression tag
Lys 175	-	expression tag
His 176	-	expression tag
His 177	-	expression tag
His 178	-	expression tag
His 179	-	expression tag
His 180	-	expression tag
His 181	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	134336.8
Non-Polymers*	Number of molecules	16
	Total formula weight	993.1
All*	Total formula weight	135329.9

*Water molecules are not included.