6PHB

Pfs25 in complex with the human transmission blocking antibody 2530

Functional Information from GO Data

Chain	GOid	namespace	contents
E	0009986	cellular_component	cell surface
E	0016020	cellular_component	membrane
I	0009986	cellular_component	cell surface
I	0016020	cellular_component	membrane

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	binding site for residue EDO I 201

Chain	Residue
I	ILE60
I	LYS72
I	CYS73
I	HOH335
I	HOH375

---

site_id	AC2
Number of Residues	5
Details	binding site for residue EDO I 202

Chain	Residue
I	HOH301
I	LEU75
I	GLY76
I	TYR77
I	ASN87

---

site_id	AC3
Number of Residues	4
Details	binding site for residue EDO C 301

Chain	Residue
C	ASN211
C	GLY213
D	LYS218
D	CYS220

---

site_id	AC4
Number of Residues	6
Details	binding site for residue EDO C 302

Chain	Residue
C	GLN38
C	PRO40
C	ALA84
C	THR85
C	LYS104
C	HOH440

---

site_id	AC5
Number of Residues	4
Details	binding site for residue EDO C 303

Chain	Residue
C	ASN31
C	ASP50
C	ASN53
C	HOH532

---

site_id	AC6
Number of Residues	9
Details	binding site for residue EDO D 501

Chain	Residue
C	SER163
C	THR179
D	PHE170
D	PRO171
D	VAL173
D	SER181
D	LEU182
D	SER183
D	HOH601

---

site_id	AC7
Number of Residues	3
Details	binding site for residue EDO D 502

Chain	Residue
D	SER131
D	SER132
D	LYS218

---

site_id	AC8
Number of Residues	2
Details	binding site for residue EDO D 503

Chain	Residue
D	LEU4
D	HOH643

---

site_id	AC9
Number of Residues	3
Details	binding site for residue EDO A 301

Chain	Residue
A	PRO120
A	ASN211
A	CYS215

---

site_id	AD1
Number of Residues	5
Details	binding site for residue EDO A 302

Chain	Residue
A	GLN38
A	PRO40
A	ALA84
A	THR85
A	LYS104

---

site_id	AD2
Number of Residues	8
Details	binding site for residue EDO A 303

Chain	Residue
A	GLN37
A	LYS39
A	PRO59
A	ARG61
A	PHE62
A	GLU81
A	ASP82
A	HOH413

---

site_id	AD3
Number of Residues	5
Details	binding site for residue EDO A 304

Chain	Residue
A	THR198
A	HIS199
A	GLN200
A	HOH452
A	HOH474

---

site_id	AD4
Number of Residues	5
Details	binding site for residue EDO A 305

Chain	Residue
A	SER122
A	ASP123
A	GLU124
B	PRO127
B	LYS213

---

site_id	AD5
Number of Residues	5
Details	binding site for residue EDO A 306

Chain	Residue
A	THR207
A	LYS208
A	SER209
B	LYS133
I	GLU143

---

site_id	AD6
Number of Residues	3
Details	binding site for residue EDO B 301

Chain	Residue
B	SER131
B	SER132
B	LYS218

---

site_id	AD7
Number of Residues	9
Details	binding site for residue EDO B 302

Chain	Residue
A	ASP50
A	HOH470
B	SER100
B	TYR101
B	SER102
B	PHE103
E	VAL41
E	LYS47
E	LYS51

---

Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YACEVTH

Chain	Residue	Details
C	TYR193-HIS199
D	TYR198-HIS204

---

site_id	PS01186
Number of Residues	14
Details	EGF_2 EGF-like domain signature 2. CkCnlGYdmvnnv..C

Chain	Residue	Details
I	CYS71-CYS84
I	CYS156-CYS171

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	58
Details	Domain: {"description":"EGF-like 1; truncated"}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	90
Details	Domain: {"description":"EGF-like 2"}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	88
Details	Domain: {"description":"EGF-like 3"}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	4
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---