6PDP
Human PIM1 bound to benzothiophene inhibitor 379
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Serine/threonine-protein kinase pim-1 | polymer | 313 | 35590.5 | 1 | UniProt (P11309) Pfam (PF00069) | Homo sapiens (Human) | |
| 2 | B (B) | Peptide | polymer | 14 | 1592.8 | 1 | synthetic construct | ||
| 3 | C (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 4 | D (A) | 5-[2-(acetylamino)-1-benzothiophen-4-yl]-N-cyclopropylthiophene-2-carboxamide | non-polymer | 356.5 | 1 | Chemie (OBY) | |||
| 5 | E, F (A, B) | water | water | 18.0 | 19 | Chemie (HOH) |
Sequence modifications
A: 1 - 312 (UniProt: P11309)
| PDB | External Database | Details |
|---|---|---|
| Ser 0 | - | expression tag |
| Gly 250 | Arg 250 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 37183.3 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 452.5 | |
| All* | Total formula weight | 37635.9 |
