6PC1
Crystal structure of Helicobacter pylori PPX/GppA (E143A) in complex with ppGpp
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | Guanosine pentaphosphate phosphohydrolase | polymer | 495 | 55597.5 | 4 | UniProt (B5ZA44) Pfam (PF02541) Pfam (PF21447) In PDB | Helicobacter pylori (strain G27) | |
2 | A, B, C, D | GUANOSINE-5',3'-TETRAPHOSPHATE | non-polymer | 603.2 | 4 | Chemie (G4P) | |||
3 | A, B, C, D | PHOSPHATE ION | non-polymer | 95.0 | 5 | Chemie (PO4) | |||
4 | A, B, C, D | (2S)-2-hydroxybutanedioic acid | non-polymer | 134.1 | 5 | Chemie (LMR) | |||
5 | A, B | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
6 | B, C | MAGNESIUM ION | non-polymer | 24.3 | 3 | Chemie (MG) | |||
7 | water | water | 18.0 | 369 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 2 - 484 (UniProt: B5ZA44)
PDB | External Database | Details |
---|---|---|
Met -10 | - | initiating methionine |
Arg -9 | - | expression tag |
Gly -8 | - | expression tag |
Ser -7 | - | expression tag |
His -6 | - | expression tag |
His -5 | - | expression tag |
His -4 | - | expression tag |
His -3 | - | expression tag |
His -2 | - | expression tag |
His -1 | - | expression tag |
Gly 0 | - | expression tag |
Ser 1 | - | expression tag |
Ala 143 | Glu 143 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 222390.0 | |
Non-Polymers* | Number of molecules | 19 |
Total formula weight | 3755.0 | |
All* | Total formula weight | 226145.0 |