6P9Z
Staphylococcus aureus Dihydrofolate reductase in complex with NADPH and Methotrexate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (X) | Dihydrofolate reductase | polymer | 157 | 18015.6 | 1 | UniProt (P0A017) Pfam (PF00186) | Staphylococcus aureus | DHFR |
| 2 | B (X) | METHOTREXATE | non-polymer | 454.4 | 1 | Chemie (MTX) | |||
| 3 | C (X) | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 1 | Chemie (NAP) | |||
| 4 | D (X) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | E (X) | water | water | 18.0 | 63 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 18015.6 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1289.9 | |
| All* | Total formula weight | 19305.5 |
