6P50
Crystal Structure of a Complex of human IL-7Ralpha with an anti-IL-7Ralpha Fab 4A10
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (C) | Interleukin-7 receptor subunit alpha | polymer | 223 | 25691.0 | 1 | UniProt (P16871) Pfam (PF18447) Pfam (PF00041) | Homo sapiens (Human) | IL-7RA,CDw127 |
| 2 | B (H) | anti-IL-7R 4A10 Fab heavy chain | polymer | 225 | 24360.2 | 1 | Mus musculus (Mouse) | ||
| 3 | C (L) | anti-IL-7R 4A10 Fab light chain | polymer | 213 | 23606.3 | 1 | Mus musculus (Mouse) | ||
| 4 | D (C) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) |
Sequence modifications
C: 1 - 219 (UniProt: P16871)
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | expression tag |
| Ser -2 | - | expression tag |
| His -1 | - | expression tag |
| Met 0 | - | expression tag |
| Thr 46 | Ile 66 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 73657.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 221.2 | |
| All* | Total formula weight | 73878.7 |
