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6P09

Human DNA Ligase 1 Bound to an Adenylated, dideoxy Terminated DNA nick with 200 mM Mg2+

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1ADNA ligase 1polymer64571786.01UniProt (P18858)
Pfam (PF04675)
Pfam (PF01068)
Pfam (PF04679)
In PDB
Homo sapiens (Human)DNA ligase I,Polydeoxyribonucleotide synthase [ATP] 1
2BDNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*TP*C)-3')polymer113365.21synthetic construct
3CDNA (5'-D(P*GP*TP*CP*GP*GP*AP*C)-3')polymer72138.41synthetic construct
4DDNA (5'-D(*GP*TP*CP*CP*GP*AP*CP*GP*AP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3')polymer185486.61synthetic construct
5A, CMAGNESIUM IONnon-polymer24.35Chemie (MG)
6ADI(HYDROXYETHYL)ETHERnon-polymer106.11Chemie (PEG)
7CADENOSINE MONOPHOSPHATEnon-polymer347.21Chemie (AMP)
8waterwater18.0562Chemie (HOH)
Sequence modifications
A: 262 - 904 (UniProt: P18858)
PDBExternal DatabaseDetails
Ser 260-expression tag
Asn 261-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight82776.2
Non-Polymers*Number of molecules7
Total formula weight574.9
All*Total formula weight83351.1
*Water molecules are not included.

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PDB entries from 2024-09-04

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