Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003909 | molecular_function | DNA ligase activity |
| A | 0003910 | molecular_function | DNA ligase (ATP) activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006281 | biological_process | DNA repair |
| A | 0006310 | biological_process | DNA recombination |
| A | 0071897 | biological_process | DNA biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 1001 |
| Chain | Residue |
| A | GLU592 |
| A | HOH1207 |
| A | HOH1285 |
| A | HOH1355 |
| B | DG11 |
| B | HOH119 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 1002 |
| Chain | Residue |
| A | HOH1498 |
| A | HOH1509 |
| A | HOH1529 |
| A | HOH1258 |
| A | HOH1308 |
| A | HOH1497 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 1003 |
| Chain | Residue |
| A | GLY799 |
| A | HOH1192 |
| A | HOH1307 |
| A | HOH1323 |
| C | DG4 |
| C | HOH222 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 1004 |
| Chain | Residue |
| A | HOH1216 |
| A | HOH1248 |
| A | HOH1510 |
| A | HOH1526 |
| A | HOH1530 |
| A | HOH1538 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue PEG A 1005 |
| Chain | Residue |
| A | ALA483 |
| A | LYS487 |
| A | TRP495 |
| A | HOH1122 |
| site_id | AC6 |
| Number of Residues | 17 |
| Details | binding site for residue AMP C 101 |
| Chain | Residue |
| A | GLU566 |
| A | TYR567 |
| A | LYS568 |
| A | TYR569 |
| A | ARG573 |
| A | ARG589 |
| A | GLU621 |
| A | PHE660 |
| A | MET723 |
| A | LYS725 |
| A | TRP742 |
| A | LYS744 |
| A | HOH1149 |
| C | DG1 |
| C | HOH202 |
| C | HOH208 |
| C | HOH209 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | binding site for residue MG C 102 |
| Chain | Residue |
| A | HOH1135 |
| A | HOH1146 |
| A | HOH1149 |
| A | HOH1335 |
| C | DG1 |
Functional Information from PROSITE/UniProt
| site_id | PS00333 |
| Number of Residues | 27 |
| Details | DNA_LIGASE_A2 ATP-dependent DNA ligase signature 2. EGLMVKtldvdat.YEiakrs.Hnwl..KLK |
| Chain | Residue | Details |
| A | GLU720-LYS746 | |
| site_id | PS00697 |
| Number of Residues | 9 |
| Details | DNA_LIGASE_A1 ATP-dependent DNA ligase AMP-binding site. EYKYDGQRA |
| Chain | Residue | Details |
| A | GLU566-ALA574 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 11 |
| Details | Region: {"description":"Interaction with target DNA"} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Active site: {"description":"N6-AMP-lysine intermediate","evidences":[{"source":"PROSITE-ProRule","id":"PRU10135","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"15565146","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1X9N","evidenceCode":"ECO:0007744"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000305"}]} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 4 |
| Details | Site: {"description":"Interaction with target DNA"} |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]} |
| site_id | SWS_FT_FI7 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]} |
