6OSP
Crystal Structure Analysis of PIP4K2A
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha | polymer | 394 | 45233.0 | 2 | UniProt (P48426) Pfam (PF01504) In PDB | Homo sapiens (Human) | 1-phosphatidylinositol 5-phosphate 4-kinase 2-alpha,Diphosphoinositide kinase 2-alpha,PIP5KIII,Phosphatidylinositol 5-phosphate 4-kinase type II alpha,PIP4KII-alpha,PtdIns(4)P-5-kinase B isoform,PtdIns(4)P-5-kinase C isoform,PtdIns(5)P-4-kinase isoform 2-alpha |
2 | A, B | 4-{[(2E)-4-(dimethylamino)but-2-enoyl]amino}-N-(3-{[6-(1H-indol-3-yl)pyrimidin-4-yl]amino}phenyl)benzamide | non-polymer | 531.6 | 2 | Chemie (N51) | |||
3 | A, B | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
4 | water | water | 18.0 | 224 | Chemie (HOH) |
Sequence modifications
A, B: 35 - 405 (UniProt: P48426)
PDB | External Database | Details |
---|---|---|
Met 12 | - | initiating methionine |
His 13 | - | expression tag |
His 14 | - | expression tag |
His 15 | - | expression tag |
His 16 | - | expression tag |
His 17 | - | expression tag |
His 18 | - | expression tag |
Ser 19 | - | expression tag |
Ser 20 | - | expression tag |
Gly 21 | - | expression tag |
Val 22 | - | expression tag |
Asp 23 | - | expression tag |
Leu 24 | - | expression tag |
Gly 25 | - | expression tag |
Thr 26 | - | expression tag |
Glu 27 | - | expression tag |
Asn 28 | - | expression tag |
Leu 29 | - | expression tag |
Tyr 30 | - | expression tag |
Phe 31 | - | expression tag |
Gln 32 | - | expression tag |
Ser 33 | - | expression tag |
Met 34 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 90466.0 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 1247.4 | |
All* | Total formula weight | 91713.4 |