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6OSP

Crystal Structure Analysis of PIP4K2A

Functional Information from GO Data
ChainGOidnamespacecontents
A0001750cellular_componentphotoreceptor outer segment
A0001917cellular_componentphotoreceptor inner segment
A0005515molecular_functionprotein binding
A0005524molecular_functionATP binding
A0005634cellular_componentnucleus
A0005654cellular_componentnucleoplasm
A0005737cellular_componentcytoplasm
A0005764cellular_componentlysosome
A0005776cellular_componentautophagosome
A0005829cellular_componentcytosol
A0005886cellular_componentplasma membrane
A0006629biological_processlipid metabolic process
A0010506biological_processregulation of autophagy
A0016301molecular_functionkinase activity
A0016308molecular_function1-phosphatidylinositol-4-phosphate 5-kinase activity
A0016309molecular_function1-phosphatidylinositol-5-phosphate 4-kinase activity
A0035855biological_processmegakaryocyte development
A0042803molecular_functionprotein homodimerization activity
A0042995cellular_componentcell projection
A0046488biological_processphosphatidylinositol metabolic process
A0046627biological_processnegative regulation of insulin receptor signaling pathway
A0046854biological_processphosphatidylinositol phosphate biosynthetic process
A0052742molecular_functionphosphatidylinositol kinase activity
A0061909biological_processautophagosome-lysosome fusion
A0090119biological_processvesicle-mediated cholesterol transport
A1902635biological_process1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process
A2000786biological_processpositive regulation of autophagosome assembly
B0001750cellular_componentphotoreceptor outer segment
B0001917cellular_componentphotoreceptor inner segment
B0005515molecular_functionprotein binding
B0005524molecular_functionATP binding
B0005634cellular_componentnucleus
B0005654cellular_componentnucleoplasm
B0005737cellular_componentcytoplasm
B0005764cellular_componentlysosome
B0005776cellular_componentautophagosome
B0005829cellular_componentcytosol
B0005886cellular_componentplasma membrane
B0006629biological_processlipid metabolic process
B0010506biological_processregulation of autophagy
B0016301molecular_functionkinase activity
B0016308molecular_function1-phosphatidylinositol-4-phosphate 5-kinase activity
B0016309molecular_function1-phosphatidylinositol-5-phosphate 4-kinase activity
B0035855biological_processmegakaryocyte development
B0042803molecular_functionprotein homodimerization activity
B0042995cellular_componentcell projection
B0046488biological_processphosphatidylinositol metabolic process
B0046627biological_processnegative regulation of insulin receptor signaling pathway
B0046854biological_processphosphatidylinositol phosphate biosynthetic process
B0052742molecular_functionphosphatidylinositol kinase activity
B0061909biological_processautophagosome-lysosome fusion
B0090119biological_processvesicle-mediated cholesterol transport
B1902635biological_process1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process
B2000786biological_processpositive regulation of autophagosome assembly
Functional Information from PDB Data
site_idAC1
Number of Residues10
Detailsbinding site for residue N51 A 4001
ChainResidue
ALYS140
AILE358
AILE143
ALYS145
ATHR196
AARG197
AASN198
AVAL199
APHE200
ALEU277

site_idAC2
Number of Residues7
Detailsbinding site for residue GOL A 4002
ChainResidue
AGLY171
AILE172
ATHR173
AGLN177
ALYS258
AVAL338
AHOH4196

site_idAC3
Number of Residues10
Detailsbinding site for residue N51 B 4001
ChainResidue
BLYS140
BILE143
BLYS145
BTHR196
BARG197
BASN198
BVAL199
BPHE200
BLEU277
BHOH4164

site_idAC4
Number of Residues7
Detailsbinding site for residue GOL B 4002
ChainResidue
BGLY171
BILE172
BTHR173
BGLN177
BLYS258
BVAL338
BHOH4171

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues4
DetailsMOD_RES: N6-acetyllysine => ECO:0007744|PubMed:19608861
ChainResidueDetails
ALYS89
ALYS145
BLYS89
BLYS145

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PDB entries from 2024-07-24

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