6OQX
Human Liver Receptor Homolog-1 bound to the agonist 5N and a fragment of the Tif2 coregulator
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Nuclear receptor subfamily 5 group A member 2 | polymer | 245 | 28330.7 | 1 | UniProt (O00482) Pfam (PF00104) In PDB | Homo sapiens (Human) | Alpha-1-fetoprotein transcription factor,B1-binding factor,hB1F,CYP7A promoter-binding factor,Hepatocytic transcription factor,Liver receptor homolog 1,LRH-1 |
| 2 | C | Nuclear receptor coactivator 2 | polymer | 15 | 1810.0 | 1 | UniProt (Q15596) In PDB | Homo sapiens | NCoA-2,Class E basic helix-loop-helix protein 75,bHLHe75,Transcriptional intermediary factor 2,hTIF2 |
| 3 | A | (8beta,11alpha,12alpha)-8-(1-phenylethenyl)-1,6:7,14-dicycloprosta-1,3,5,7(14)-tetraen-11-yl sulfamate | non-polymer | 465.6 | 1 | Chemie (N1V) | |||
| 4 | water | water | 18.0 | 71 | Chemie (HOH) |
Sequence modifications
A: 299 - 541 (UniProt: O00482)
| PDB | External Database | Details |
|---|---|---|
| Ser 297 | - | expression tag |
| Asn 298 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 30140.7 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 465.6 | |
| All* | Total formula weight | 30606.4 |
