6OPH
phosphorylated ERK2 with GDC-0994
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Mitogen-activated protein kinase 1 | polymer | 354 | 41134.0 | 1 | UniProt (P28482) Pfam (PF00069) | Homo sapiens (Human) | MAPK 1,ERT1,Extracellular signal-regulated kinase 2,ERK-2,MAP kinase isoform p42,p42-MAPK,Mitogen-activated protein kinase 2,MAPK 2 |
| 2 | B (A) | 1-[(1~{S})-1-(4-chloranyl-3-fluoranyl-phenyl)-2-oxidanyl-ethyl]-4-[2-[(2-methylpyrazol-3-yl)amino]pyrimidin-4-yl]pyridin-2-one | non-polymer | 440.9 | 1 | Chemie (6QB) | |||
| 3 | C (A) | water | water | 18.0 | 17 | Chemie (HOH) |
Sequence modifications
A: 6 - 358 (UniProt: P28482)
| PDB | External Database | Details |
|---|---|---|
| Ser 5 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 41134.0 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 440.9 | |
| All* | Total formula weight | 41574.9 |
