6OAU
Apo Structure of WT Lipoprotein Lipase in Complex with GPIHBP1 Mutant N78D N82D produced in GnTI-deficient HEK293-F cells
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Lipoprotein lipase | polymer | 448 | 50465.1 | 2 | UniProt (P06858) Pfam (PF00151) Pfam (PF01477) | Homo sapiens (Human) | LPL |
| 2 | C, D (C, D) | Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1 | polymer | 131 | 14727.8 | 2 | UniProt (Q8IV16) Pfam (PF00021) | Homo sapiens (Human) | GPI-anchored HDL-binding protein 1,High density lipoprotein-binding protein 1 |
| 3 | E, F, I, J (A, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 4 | Chemie (NAG) | |||
| 4 | G (A) | MALONATE ION | non-polymer | 102.0 | 1 | Chemie (MLI) | |||
| 5 | H, K (A, B) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 6 | L, M, N, O (A, B, C, D) | water | water | 18.0 | 83 | Chemie (HOH) |
Sequence modifications
C, D: 21 - 151 (UniProt: Q8IV16)
| PDB | External Database | Details |
|---|---|---|
| Asp 78 | Asn 78 | engineered mutation |
| Asp 82 | Asn 82 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 130385.8 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1067.0 | |
| All* | Total formula weight | 131452.8 |
