6O1F

Complex between soybean trypsin inhibitor beta1-tryptase and a humanized fab

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Tryptase alpha/beta-1	polymer	260	29211.1	1	UniProt (Q15661) Pfam (PF00089)	Homo sapiens (Human)	Tryptase-1,Tryptase I,Tryptase alpha-1
2	B (H)	Heavy Chain hu31A.v11	polymer	227	24361.2	1		Homo sapiens
3	C (I)	Trypsin inhibitor A	polymer	192	21328.0	1	UniProt (P01070) Pfam (PF00197)	Glycine max (Soybean)	Kunitz-type trypsin inhibitor A
4	D (L)	Light Chain hu31A.v11	polymer	213	23451.9	1		Homo sapiens
5	E, F (I)	1,2-ETHANEDIOL	non-polymer		62.1	2	Chemie (EDO)
6	G, H, I, J (A, H, I, L)	water	water		18.0	441	Chemie (HOH)

Sequence modifications

A: 16 - 246 (UniProt: Q15661)

PDB	External Database	Details
Ala 1	-	expression tag
Gly 2	-	expression tag
Ser 3	-	expression tag
Thr 4	-	expression tag
His 5	-	expression tag
His 6	-	expression tag
His 7	-	expression tag
His 8	-	expression tag
His 9	-	expression tag
His 10	-	expression tag
Asp 11	-	expression tag
Asp 12	-	expression tag
Asp 13	-	expression tag
Asp 14	-	expression tag
Lys 15	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	98352.2
Non-Polymers*	Number of molecules	2
	Total formula weight	124.1
All*	Total formula weight	98476.4

*Water molecules are not included.