6NT2
type 1 PRMT in complex with the inhibitor GSK3368715
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, D, B, C) | Protein arginine N-methyltransferase 1 | polymer | 371 | 42511.6 | 4 | UniProt (Q99873) Pfam (PF13649) Pfam (PF22528) | Homo sapiens (Human) | Histone-arginine N-methyltransferase PRMT1,Interferon receptor 1-bound protein 4 |
| 2 | E, EA, N, V (A, C, D, B) | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 4 | Chemie (SAH) PubChem (16760024) PubChem (25210495) PubChem (177678424) PubChem (21125603) PubChem (25203782) PubChem (52224400) PubChem (44361184) PubChem (46936206) PubChem (50989525) PubChem (51380914) PubChem (6419189) PubChem (52224398) PubChem (57544532) PubChem (164157219) PubChem (59046843) PubChem (59170628) PubChem (59576228) PubChem (66805708) PubChem (70689219) PubChem (70702054) PubChem (70832431) PubChem (118374891) PubChem (118560068) PubChem (193) PubChem (13792) PubChem (189149) PubChem (439155) PubChem (5284331) PubChem (126969526) PubChem (71170554) PubChem (129105892) PubChem (13231890) PubChem (143518505) PubChem (154578335) PubChem (163054214) PubChem (163335525) | |||
| 3 | F, FA, O, W (A, C, D, B) | N~1~-({5-[4,4-bis(ethoxymethyl)cyclohexyl]-1H-pyrazol-4-yl}methyl)-N~1~,N~2~-dimethylethane-1,2-diamine | non-polymer | 366.5 | 4 | Chemie (KZS) | |||
| 4 | AA, BA, CA, G, GA... (B, A, C, D) | GLYCEROL | non-polymer | 92.1 | 23 | Chemie (GOL) PubChem (753) | |||
| 5 | DA (B) | 2,3-DIHYDROXY-1,4-DITHIOBUTANE | non-polymer | 154.3 | 1 | Chemie (DTT) | |||
| 6 | KA, LA, MA, NA (A, D, B, C) | water | water | 18.0 | 664 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 170046.2 | |
| Non-Polymers* | Number of molecules | 32 |
| Total formula weight | 5276.2 | |
| All* | Total formula weight | 175322.4 |
