6NR2
Cryo-EM structure of the TRPM8 ion channel in complex with the menthol analog WS-12 and PI(4,5)P2
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | Transient receptor potential cation channel subfamily M member 8 | polymer | 1135 | 130078.5 | 4 | Ficedula albicollis (Collared flycatcher) | ||
2 | A, B, C, D | (2S)-1-{[(R)-hydroxy{[(1R,2R,3S,4R,5R,6S)-2,3,6-trihydroxy-4,5-bis(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}-3-(octadecanoyloxy)propan-2-yl icosa-5,8,11,14-tetraenoate | non-polymer | 1047.1 | 4 | Chemie (KXP) | |||
3 | A, B, C, D | (1R,2S,5R)-N-(4-methoxyphenyl)-5-methyl-2-(propan-2-yl)cyclohexane-1-carboxamide | non-polymer | 289.4 | 4 | Chemie (KXS) |
Sequence modifications
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 520313.8 | |
Non-Polymers* | Number of molecules | 8 |
Total formula weight | 5346.0 | |
All* | Total formula weight | 525659.8 |